SCHEMBL2921730

SCHEMBL2921730

C=CCOc1c(C(C)(C)C)cc(C(C)(C)C)cc1[Si](C)(C)C1C=C(N2CCCCC2)c2ccccc21

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RARA P10276 1/20 0.30
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
RXRG P48443 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2924250 0.99 RARA (0.31) RARARXRARXRBRXRG
SCHEMBL2922696 0.92 MAPT (0.31) HRH3
SCHEMBL2921721 0.91 CXCR5 (0.31)
SCHEMBL2924295 0.91 CYP3A4 (0.31)
SCHEMBL2921312 0.90 HRH3 (0.31) HRH3
SCHEMBL2924611 0.90 CXCR5 (0.31)
SCHEMBL2916267 0.89 ELANE (0.30)
SCHEMBL2915297 0.89 ALDH1A1 (0.32)
SCHEMBL2924434 0.88 ALDH1A1 (0.32)
SCHEMBL2923913 0.83 MAPT (0.31) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1475383-B1 TRANSITION METAL COMPLEXES, LIGANDS, POLYMERIZATION CATALYSTS FOR OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS SUMITOMO CHEMICAL CO (JP) 2010-09-08 EP disclosed
US-7241927-B2 Transition metal complexes, ligands, catalysts for olefin polymerization, and process for production of olefin polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-07-10 US disclosed
US-7141690-B2 Transition metal complexes, ligands, polymerization catalysts for olefins, and process for production of olefin polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-11-28 US disclosed
US-20060111525-A1 Transition metal complexes, ligands, catalysts for olefin polymerization, and process for production of olefin polymers HANAOKA HIDENORI 2006-05-25 US disclosed
US-20050154158-A1 Transition metal complexes, ligands, polymerization catalysts for olefins, and process for production of olefin polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-14 US disclosed
EP-1475383-A1 TRANSITION METAL COMPLEXES, LIGANDS, POLYMERIZATION CATALYSTS FOR OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS Sumitomo Chemical Company, Limited (JP) 2004-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050154158-A1 Transition metal complexes, ligands, polymerization catalysts for olefins, and process for production of olefin polymers PYM1, OR10J3, AP1M1 RARA 2122/4885RXRA 682/4885RXRB 458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.