Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 20/20 | 0.58 |
| ▸ | MAP3K7 | O43318 | 4/20 | 0.54 |
| ▸ | MAP3K6 | O95382 | 4/20 | 0.54 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | TYK2 | P29597 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30269941 | 1.00 | MAP3K5 (0.58) | MAP3K5MAP3K7MAP3K6CCNA2CCNE1 | |
| SCHEMBL20523134 | 1.00 | MAP3K5 (0.58) | MAP3K5MAP3K7MAP3K6CCNA2CCNE1 | |
| SCHEMBL20523136 | 1.00 | MAP3K5 (0.58) | MAP3K5MAP3K7MAP3K6CCNA2CCNE1 | |
| SCHEMBL20802806 | 0.90 | MAP3K5 (0.49) | MAP3K5MAP3K7MAP3K6CCNA2CCNE1 | |
| SCHEMBL20802747 | 0.90 | MAP3K5 (0.60) | MAP3K5MAP3K7MAP3K6CCNA2CCNE1 | |
| SCHEMBL28369638 | 0.90 | MAP3K5 (0.60) | MAP3K5MAP3K7MAP3K6CCNA2CCNE1 | |
| SCHEMBL20802849 | 0.87 | MAP3K5 (0.53) | MAP3K5MAP3K7MAP3K6CCNA2CCNE1 | |
| SCHEMBL20802753 | 0.87 | MAP3K5 (0.53) | MAP3K5MAP3K7MAP3K6CCNA2CCNE1 | |
| SCHEMBL20501037 | 0.86 | MAP3K5 (0.58) | MAP3K5MAP3K7MAP3K6CDK2 | |
| SCHEMBL20501035 | 0.86 | MAP3K5 (0.58) | MAP3K5MAP3K7MAP3K6CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756785-A | Preparation and application of N- (pyridine-2-yl) benzo [ b ] five-membered heterocycle-3-carboxamide structure compound | 江西中医药大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-116874468-A | Synthesis and application of small molecular compound with 2-pyridine substituted formamide structure | 江西中医药大学 | 2023-10-13 | — | — | CN | disclosed |