Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 2/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | LYN | P07948 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | FRK | P42685 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.33 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30162787 | 1.00 | BUB1 (0.35) | BUB1DGAT2AURKAAURKBRXRA | |
| SCHEMBL29218181 | 0.88 | AURKA (0.35) | DGAT2AURKAAURKBRXRARXRB | |
| SCHEMBL30162740 | 0.88 | AURKA (0.35) | DGAT2AURKAAURKBRXRARXRB | |
| SCHEMBL30163078 | 0.83 | DHX9 (0.35) | DGAT2AURKBRXRARXRBRXRG | |
| SCHEMBL29218264 | 0.83 | DHX9 (0.35) | DGAT2AURKBRXRARXRBRXRG | |
| SCHEMBL30163046 | 0.83 | RXRA (0.34) | DGAT2RXRARXRBRXRG | |
| SCHEMBL30163108 | 0.81 | BUB1 (0.38) | BUB1MAPK14LYNDYRK1AGSK3B | |
| SCHEMBL29218235 | 0.81 | BUB1 (0.38) | BUB1MAPK14LYNDYRK1AGSK3B | |
| SCHEMBL31216565 | 0.81 | KDM4C (0.36) | DGAT2RXRARXRBRXRGMAPK1 | |
| SCHEMBL30162958 | 0.80 | RXRA (0.32) | RXRARXRBRXRGEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118055926-A | ROCK2 inhibitors and uses thereof | 哈佛大学的校长及成员们 | 2024-05-17 | — | — | CN | disclosed |