Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.35 |
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30162865 | 1.00 | RXRA (0.40) | RXRARXRBRXRGPIK3CAMTOR | |
| SCHEMBL30162769 | 0.86 | RXRA (0.42) | RXRARXRBRXRGPIK3CAPRKDC | |
| SCHEMBL29218268 | 0.86 | RXRA (0.42) | RXRARXRBRXRGPIK3CAPRKDC | |
| SCHEMBL30163129 | 0.82 | RXRA (0.41) | RXRARXRBRXRGPIK3CAMTOR | |
| SCHEMBL30163104 | 0.81 | RXRA (0.43) | RXRARXRBRXRGPIK3CAMTOR | |
| SCHEMBL29218302 | 0.81 | RXRA (0.43) | RXRARXRBRXRGPIK3CAMTOR | |
| SCHEMBL30163039 | 0.80 | RXRA (0.42) | RXRARXRBRXRGMEN1ALDH1A1 | |
| SCHEMBL29218355 | 0.80 | RXRA (0.42) | RXRARXRBRXRGMEN1ALDH1A1 | |
| SCHEMBL5413224 | 0.78 | RXRA (0.54) | RXRARXRBRXRGALDH1A1MAPT | |
| SCHEMBL30162972 | 0.78 | KDM4E (0.45) | RXRARXRBRXRGMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118055926-A | ROCK2 inhibitors and uses thereof | 哈佛大学的校长及成员们 | 2024-05-17 | — | — | CN | disclosed |