Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30163039 | 1.00 | RXRA (0.42) | RXRARXRBRXRGMAPK8MAPK10 | |
| SCHEMBL30162769 | 0.82 | RXRA (0.42) | RXRARXRBRXRGMAPK8MAPK10 | |
| SCHEMBL29218268 | 0.82 | RXRA (0.42) | RXRARXRBRXRGMAPK8MAPK10 | |
| SCHEMBL29218286 | 0.81 | RXRA (0.41) | RXRARXRBRXRGMAPK8MAPK10 | |
| SCHEMBL30163067 | 0.81 | RXRA (0.41) | RXRARXRBRXRGMAPK8MAPK10 | |
| SCHEMBL30162841 | 0.80 | RXRA (0.41) | RXRARXRBRXRGMAPK8MAPK10 | |
| SCHEMBL29218215 | 0.80 | RXRA (0.41) | RXRARXRBRXRGMAPK8MAPK10 | |
| SCHEMBL30162865 | 0.80 | RXRA (0.40) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL29218317 | 0.80 | RXRA (0.40) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL30163082 | 0.78 | RXRA (0.39) | RXRARXRBRXRGMAPK8MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118055926-A | ROCK2 inhibitors and uses thereof | 哈佛大学的校长及成员们 | 2024-05-17 | — | — | CN | disclosed |