Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 16/20 | 0.62 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.56 |
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | STAT6 | P42226 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30892306 | 1.00 | SIRT5 (0.62) | SIRT5ZAP70SYKRAB9ANPSR1 | |
| SCHEMBL30892310 | 0.88 | SYK (0.62) | ZAP70SYKMAPK8STAT6 | |
| SCHEMBL29218434 | 0.88 | SYK (0.62) | ZAP70SYKMAPK8STAT6 | |
| SCHEMBL30892299 | 0.85 | FLT3 (0.52) | SIRT5ZAP70SYK | |
| SCHEMBL29218498 | 0.85 | FLT3 (0.52) | SIRT5ZAP70SYK | |
| SCHEMBL4714679 | 0.82 | SIRT5 (0.66) | SIRT5SYKRAB9ANPSR1 | |
| SCHEMBL15059193 | 0.80 | SIRT5 (0.55) | SIRT5ZAP70SYKRAB9ANPSR1 | |
| SCHEMBL30892315 | 0.79 | SYK (0.64) | SIRT5SYKRAB9ANPSR1 | |
| SCHEMBL6641476 | 0.79 | SYK (0.64) | SIRT5SYKRAB9ANPSR1 | |
| SCHEMBL11083131 | 0.79 | RAB9A (0.51) | SIRT5RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886798-A | Substituted benzimidazoles and use thereof | 河南中医药大学 | 2024-04-16 | — | — | CN | disclosed |