Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29218597 | 0.81 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL29218824 | 0.81 | SMYD3 (0.43) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL29218839 | 0.80 | USP2 (0.44) | RAB9ANPC1LMNAHTTKMT2A | |
| SCHEMBL30278975 | 0.79 | NPC1 (0.43) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL25039615 | 0.79 | NPC1 (0.43) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL29218796 | 0.79 | RAB9A (0.44) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL29218799 | 0.78 | PTGIR (0.49) | RAB9ANPC1SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL29218897 | 0.77 | HAO1 (0.45) | RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL29218546 | 0.77 | PRSS1 (0.39) | KMT2AMEN1 | |
| SCHEMBL25042029 | 0.76 | NPC1 (0.46) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076581-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-24 | — | — | CN | disclosed |