Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 9/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29218639 | 0.83 | EPHX1 (0.41) | EPHX1EPHX2MAPTSPHK1CA12 | |
| SCHEMBL29218805 | 0.81 | MAPT (0.37) | MAPTKMT2A | |
| SCHEMBL29218799 | 0.81 | PTGIR (0.49) | EPHX2 | |
| SCHEMBL29218556 | 0.81 | L3MBTL1 (0.49) | EPHX1EPHX2MAPTMEN1KMT2A | |
| SCHEMBL29218762 | 0.81 | EPHX1 (0.41) | EPHX1EPHX2MAPTMEN1KMT2A | |
| SCHEMBL25042050 | 0.80 | KMT2A (0.41) | EPHX1EPHX2MAPTMEN1KMT2A | |
| SCHEMBL25042055 | 0.79 | EPHX1 (0.41) | EPHX1EPHX2MAPTSPHK1 | |
| SCHEMBL29218839 | 0.79 | USP2 (0.44) | MAPTKMT2A | |
| SCHEMBL29218696 | 0.79 | MGLL (0.44) | EPHX2 | |
| SCHEMBL25039640 | 0.78 | EPHX1 (0.39) | EPHX1EPHX2SPHK1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076581-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-24 | — | — | CN | disclosed |