SCHEMBL29218643

SCHEMBL29218643

Cc1ccc(C2(N)CCC(N)CC2)cc1C

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 1/20 0.39
CYP2C19 P33261 1/20 0.35
CCR2 P41597 2/20 0.34
ALDH1A1 P00352 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31008897 1.00 OPRL1 (0.39) OPRL1CYP2C19CCR2ALDH1A1ESR1
SCHEMBL29218567 0.82 OPRL1 (0.34) OPRL1
SCHEMBL29218761 0.82 OPRL1 (0.34) OPRL1
SCHEMBL29218609 0.81 OPRL1 (0.37) OPRL1
SCHEMBL31008933 0.79 MAOB (0.47) OPRL1
SCHEMBL29218809 0.76 OPRL1 (0.33) OPRL1
SCHEMBL29218544 0.76 OPRM1 (0.38) OPRL1ALDH1A1
SCHEMBL29218856 0.75 SLC6A3 (0.44) OPRL1
SCHEMBL31008877 0.75 SLC6A3 (0.44) OPRL1
SCHEMBL31008963 0.74 SMYD3 (0.42) OPRL1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118076581-A Iron death modulators, their preparation and use 维泰瑞隆有限公司 2024-05-24 CN disclosed