Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29218626 | 0.87 | NPC1 (0.34) | GFERALDH1A1USP2MAPTNPC1 | |
| SCHEMBL29218634 | 0.87 | MAPT (0.39) | GFERALDH1A1USP2MAPTNPC1 | |
| SCHEMBL29218616 | 0.85 | NPY5R (0.35) | GFERALDH1A1USP2MAPTNPC1 | |
| SCHEMBL29218593 | 0.82 | KCNQ3 (0.47) | ALDH1A1NPC1RAB9A | |
| SCHEMBL29218774 | 0.81 | MAPT (0.35) | ALDH1A1USP2MAPTNPC1RAB9A | |
| SCHEMBL29218839 | 0.80 | USP2 (0.44) | GFERALDH1A1USP2MAPTNPC1 | |
| SCHEMBL29218716 | 0.80 | ALDH1A1 (0.43) | GFERALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL29218753 | 0.80 | HTT (0.45) | MAPTNPC1RAB9ALMNAHTT | |
| SCHEMBL29218828 | 0.78 | EPHX2 (0.45) | NPC1RAB9A | |
| SCHEMBL29218851 | 0.78 | POLB (0.46) | ALDH1A1NPC1RAB9ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076581-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-24 | — | — | CN | disclosed |