Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTR1E | P28566 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29218635 | 0.87 | EPHX2 (0.40) | HTTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL29218821 | 0.81 | LTA4H (0.50) | HTTRAB9AHPGDMAPTNPC1 | |
| SCHEMBL29218593 | 0.81 | KCNQ3 (0.47) | RAB9AHPGDMEN1KMT2ANPC1 | |
| SCHEMBL29256183 | 0.81 | ALDH1A1 (0.50) | HTTRAB9AHPGDDPP8DPP9 | |
| SCHEMBL29218644 | 0.80 | GFER (0.45) | HTTRAB9ALMNAMAPTNPC1 | |
| SCHEMBL29218716 | 0.79 | ALDH1A1 (0.43) | RAB9ALMNAMAPTNPC1EPHX1 | |
| SCHEMBL28487447 | 0.77 | EPHX2 (0.45) | RAB9AMEN1KMT2ANPC1EPHX1 | |
| SCHEMBL29218828 | 0.77 | EPHX2 (0.45) | RAB9AMEN1KMT2ANPC1EPHX1 | |
| SCHEMBL29218851 | 0.77 | POLB (0.46) | RAB9ALMNANPC1EPHX1FAAH | |
| SCHEMBL25039415 | 0.76 | KDM1A (0.52) | HTTRAB9AHPGDDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076581-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-24 | — | — | CN | disclosed |