Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25041455 | 0.80 | DRD2 (0.36) | MAPTHRH3ALDH1A1CCR5NPC1 | |
| SCHEMBL29218591 | 0.80 | MAPT (0.40) | MAPTHRH3ALDH1A1HTTHPGD | |
| SCHEMBL29218611 | 0.80 | HRH3 (0.36) | MAPTHRH3ALDH1A1CNR2 | |
| SCHEMBL31205891 | 0.77 | ALDH1A1 (0.40) | MAPTHRH3ALDH1A1HTTCCR5 | |
| SCHEMBL25039629 | 0.77 | CNR2 (0.36) | MAPTHRH3NPC1RAB9ACNR2 | |
| SCHEMBL25042037 | 0.76 | MAPT (0.49) | MAPTALDH1A1HTTNPC1MAPK1 | |
| SCHEMBL29218547 | 0.76 | MAPT (0.36) | MAPTHRH3ALDH1A1HTTHPGD | |
| SCHEMBL29218846 | 0.75 | CNR2 (0.36) | MAPTHRH3ALDH1A1HTTHPGD | |
| SCHEMBL29218861 | 0.75 | CNR2 (0.39) | MAPTHRH3ALDH1A1HTTHPGD | |
| SCHEMBL29218530 | 0.74 | CNR2 (0.39) | MAPTHRH3ALDH1A1HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076581-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-24 | — | — | CN | disclosed |