SCHEMBL29219201

SCHEMBL29219201

O=c1[nH][nH]c2ncc(F)cc12

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DAO P14920 5/20 0.41
PARP1 P09874 1/20 0.37
DDO Q99489 1/20 0.36
PADI4 Q9UM07 3/20 0.33
XDH P47989 1/20 0.33
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30826139 1.00 DAO (0.41) DAOPARP1DDOPADI4XDH
SCHEMBL7554127 0.77 KDM4E (0.42) DAOPARP1DDOPADI4XDH
SCHEMBL24566409 0.76 DYRK1A (0.47) ALDH1A1
SCHEMBL15785416 0.76 PARP1 (0.37) PARP1PADI4
SCHEMBL14820336 0.72 KDM4E (0.33) ALDH1A1GAA
SCHEMBL14805792 0.68 KDM4E (0.37) DAO
SCHEMBL669933 0.68 AXL (0.42) PARP1ALDH1A1
SCHEMBL29547282 0.67 ADORA2A (0.34) XDHALDH1A1
SCHEMBL4219276 0.67 ADORA2A (0.34) XDHALDH1A1
SCHEMBL11202110 0.66 AXL (0.51) ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117946096-A Vitamin Li Xigu intermediate and preparation method thereof 上海医药工业研究院有限公司 2024-04-30 CN disclosed
CN-117946097-A Vitamin Li Xigu, intermediate thereof and preparation method 上海医药工业研究院有限公司 2024-04-30 CN disclosed