SCHEMBL29220172

SCHEMBL29220172

C=CCOC(=O)c1ccc(O)cc1C(=O)OCC=C

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.66
ALDH1A1 P00352 2/20 0.53
HSD17B10 Q99714 2/20 0.53
TSHR P16473 1/20 0.53
SERPINE1 P05121 1/20 0.50
CA12 O43570 6/20 0.47
CA1 P00915 6/20 0.47
CA2 P00918 6/20 0.47
CA7 P43166 6/20 0.47
CA9 Q16790 6/20 0.47
CA14 Q9ULX7 6/20 0.47
KDM4E B2RXH2 1/20 0.47
TP53 P04637 1/20 0.47
HPGD P15428 1/20 0.47
SNCA P37840 1/20 0.41
APP P05067 1/20 0.41
PDK2 Q15119 1/20 0.40
PDK4 Q16654 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2966217 0.88 CA12 (0.63) CYP3A4ALDH1A1HSD17B10TSHRSERPINE1
SCHEMBL2925752 0.88 SERPINE1 (0.67) CYP3A4ALDH1A1HSD17B10TSHRSERPINE1
SCHEMBL9124680 0.85 CYP3A4 (0.56) CYP3A4ALDH1A1HSD17B10TSHRSERPINE1
SCHEMBL9127373 0.85 CYP3A4 (0.56) CYP3A4ALDH1A1HSD17B10TSHRSERPINE1
SCHEMBL10487043 0.84 CYP3A4 (0.68) CYP3A4ALDH1A1HSD17B10TSHRKDM4E
SCHEMBL10693946 0.84 CYP3A4 (0.54) CYP3A4ALDH1A1HSD17B10TSHRSERPINE1
SCHEMBL209680 0.83 CYP3A4 (0.70) CYP3A4ALDH1A1HSD17B10TSHRKDM4E
SCHEMBL48751 0.83 CYP3A4 (0.66) CYP3A4ALDH1A1HSD17B10TSHRCA12
SCHEMBL29376657 0.83 CYP3A4 (0.66) CYP3A4ALDH1A1HSD17B10TSHRCA12
SCHEMBL9124017 0.82 CYP3A4 (0.51) CYP3A4ALDH1A1HSD17B10TSHRSERPINE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108878-A Organic polymer carrier and preparation method and application thereof 中国石油天然气股份有限公司 2024-05-31 CN claimed
CN-118108889-A Organic polymer carrier, Z-N catalyst, and preparation method and application thereof 中国石油天然气股份有限公司 2024-05-31 CN claimed
CN-118108878-A Organic polymer carrier and preparation method and application thereof 中国石油天然气股份有限公司 2024-05-31 CN disclosed
CN-118108889-A Organic polymer carrier, Z-N catalyst, and preparation method and application thereof 中国石油天然气股份有限公司 2024-05-31 CN disclosed