Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29035782 | 0.91 | HSD17B10 (0.60) | CYP3A4HSD17B10ALDH1A1TSHRSERPINE1 | |
| SCHEMBL10336950 | 0.85 | HSD17B10 (0.55) | CYP3A4HSD17B10ALDH1A1TSHRKDM4E | |
| SCHEMBL787324 | 0.85 | CYP3A4 (0.54) | CYP3A4HSD17B10ALDH1A1TSHRKDM4E | |
| SCHEMBL29220172 | 0.84 | CYP3A4 (0.66) | CYP3A4HSD17B10ALDH1A1TSHRSERPINE1 | |
| SCHEMBL7207362 | 0.84 | CYP3A4 (0.53) | CYP3A4HSD17B10ALDH1A1TSHRKDM4E | |
| SCHEMBL29230369 | 0.83 | CA12 (0.56) | CYP3A4HSD17B10ALDH1A1CA12CA1 | |
| SCHEMBL2925752 | 0.83 | SERPINE1 (0.67) | CYP3A4HSD17B10ALDH1A1TSHRSERPINE1 | |
| SCHEMBL3089041 | 0.81 | HSD17B1 (0.50) | CYP3A4ALDH1A1CA12CA1CA2 | |
| SCHEMBL1908071 | 0.80 | ALDH1A1 (0.52) | HSD17B10ALDH1A1TSHRCA12CA1 | |
| SCHEMBL7806960 | 0.80 | GABRA1 (0.43) | ALDH1A1TSHRSERPINE1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4727103-A | IMPROVED OXIDATION RESISTANCE | MALLINCKRODT, INC. (US) | 1988-02-23 | — | — | US | disclosed |
| EP-0076067-B1 | ISOCYANURIC ACID DERIVATIVES, THEIR PREPARATION AND USE IN STABILIZING ORGANIC SUBSTANCES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-01-07 | — | — | EP | disclosed |
| US-4680325-A | Anti-oxidant isocyanurate ester of thioamidophenol and polyolefins stabilized therewith | MALLINCKRODT, INC. (US) | 1987-07-14 | — | — | US | disclosed |
| US-4569959-A | OXIDATION RESISTANCE, HEAT RESISTANCE | MALLINCKRODT, INC. (US) | 1986-02-11 | — | — | US | disclosed |