Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29220172 | 0.82 | CYP3A4 (0.66) | CYP3A4ALDH1A1HSD17B10TSHRSERPINE1 | |
| SCHEMBL9127373 | 0.81 | CYP3A4 (0.56) | CYP3A4ALDH1A1HSD17B10TSHRSERPINE1 | |
| SCHEMBL14780479 | 0.81 | CYP3A4 (0.70) | CYP3A4ALDH1A1HSD17B10TSHRLMNA | |
| SCHEMBL2925752 | 0.80 | SERPINE1 (0.67) | CYP3A4ALDH1A1HSD17B10TSHRSERPINE1 | |
| SCHEMBL9124680 | 0.78 | CYP3A4 (0.56) | CYP3A4ALDH1A1HSD17B10TSHRSERPINE1 | |
| SCHEMBL2966217 | 0.77 | CA12 (0.63) | CYP3A4ALDH1A1HSD17B10TSHRSERPINE1 | |
| SCHEMBL663178 | 0.77 | TDP1 (0.55) | CYP3A4ALDH1A1TSHRSERPINE1ESRRG | |
| SCHEMBL10693946 | 0.77 | CYP3A4 (0.54) | CYP3A4ALDH1A1HSD17B10TSHRSERPINE1 | |
| SCHEMBL13117667 | 0.76 | TSHR (0.54) | CYP3A4ALDH1A1HSD17B10TSHRSERPINE1 | |
| SCHEMBL1940800 | 0.75 | CA12 (0.61) | ALDH1A1HSD17B10TSHRKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468897-A | Bi-aromatic esters, a process for their preparation and their use in human or veterinary medicine and in cosmetic compositions | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1995-11-21 | — | — | US | disclosed |
| US-5332856-A | Treatment of a dermatologic, rheumatismal, respiratory or ophthalmologic ailment | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1994-07-26 | — | — | US | disclosed |
| US-5200550-A | Administering for dermatologic, rheumatismal, respiratory or ophthalomologic disorders | CENTRE INTERNATIONAL DE RECHERCES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1993-04-06 | — | — | US | disclosed |