SCHEMBL29220219

SCHEMBL29220219

C=CCC(C)(C(=O)O)C(=O)OCCCCC

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.42
TSHR P16473 6/20 0.42
HPGD P15428 1/20 0.42
NAAA Q02083 1/20 0.40
EPHX1 P07099 1/20 0.38
ATM Q13315 1/20 0.37
PLA2G2C Q5R387 1/20 0.35
ALDH1A1 P00352 3/20 0.35
CYP3A4 P08684 2/20 0.35
TP53 P04637 1/20 0.35
MAPK1 P28482 1/20 0.35
RAD52 P43351 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28556865 0.92 TSHR (0.46) HCAR2TSHRHPGDNAAAEPHX1
SCHEMBL29220174 0.90 TSHR (0.46) HCAR2TSHRHPGDNAAAEPHX1
SCHEMBL29220217 0.90 TSHR (0.46) HCAR2TSHRHPGDNAAAEPHX1
SCHEMBL28123787 0.87 TSHR (0.52) HCAR2TSHRHPGDNAAAEPHX1
SCHEMBL28004303 0.83 TSHR (0.47) HCAR2TSHRHPGDNAAAATM
SCHEMBL3181065 0.82 MMP8 (0.41) HCAR2TSHRALDH1A1CYP3A4MAPK1
SCHEMBL28480624 0.82 NAAA (0.46) HCAR2TSHRNAAAEPHX1ATM
SCHEMBL15622017 0.81 TSHR (0.44) HCAR2TSHRHPGDNAAAEPHX1
SCHEMBL28554034 0.80 TSHR (0.47) HCAR2TSHRHPGDNAAAEPHX1
SCHEMBL28133892 0.80 TSHR (0.37) HCAR2TSHRHPGDATMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108878-A Organic polymer carrier and preparation method and application thereof 中国石油天然气股份有限公司 2024-05-31 CN claimed
CN-118108878-A Organic polymer carrier and preparation method and application thereof 中国石油天然气股份有限公司 2024-05-31 CN disclosed