Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.53 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | RORC | P51449 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | FASN | P49327 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31432270 | 0.81 | RORC (0.50) | SLC6A9SLC6A5RORCHPGDHTT | |
| SCHEMBL12813152 | 0.81 | KMT2A (0.58) | MEN1KMT2AHPGDHTTCNR1 | |
| SCHEMBL19894129 | 0.79 | GBA1 (0.42) | SLC6A9SLC6A5HTTFASN | |
| SCHEMBL2529453 | 0.78 | MEN1 (0.55) | MEN1KMT2AHPGDHTTCNR1 | |
| SCHEMBL17979877 | 0.78 | MEN1 (0.55) | MEN1KMT2AHPGDHTTCNR1 | |
| SCHEMBL7895681 | 0.78 | MEN1 (0.55) | MEN1KMT2AHPGDHTTCNR1 | |
| SCHEMBL29717082 | 0.78 | RAB9A (0.57) | SLC6A5MEN1KMT2AHPGDHTT | |
| SCHEMBL4202320 | 0.77 | FASN (0.57) | FASN | |
| SCHEMBL21524887 | 0.76 | PHGDH (0.63) | KMT2AHPGDHTTPKM | |
| SCHEMBL12545691 | 0.76 | HSP90AA1 (0.53) | MEN1KMT2AHPGDHTTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117915903-A | Compounds for the treatment of neurodegenerative, degenerative and metabolic disorders and uses thereof | 佛罗里达大学研究基金会公司 | 2024-04-19 | — | — | CN | disclosed |
| EP-4259118-A1 | COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE, DEGENERATIVE AND METABOLIC DISORDERS | The Scripps Research Institute (US) | 2023-10-18 | — | — | EP | disclosed |
| WO-2022125989-A1 | COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE, DEGENERATIVE AND METABOLIC DISORDERS | SCRIPPS RESEARCH INSTITUTE, THE (US) | 2022-06-16 | — | — | WO | disclosed |