Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22408797 | 0.85 | KDM4E (0.53) | HPGDKDM4EL3MBTL1NR4A1NR4A2 | |
| Benzene SCHEMBL28284945 | 0.83 | NR4A1 (0.67) | HPGDKDM4EL3MBTL1NR4A1NR4A2 | |
| SCHEMBL29459734 | 0.81 | NR4A1 (0.63) | HPGDKDM4EL3MBTL1NR4A1NR4A2 | |
| SCHEMBL137605 | 0.81 | NR4A1 (0.63) | HPGDKDM4EL3MBTL1NR4A1NR4A2 | |
| SCHEMBL10781207 | 0.80 | ALDH1A1 (0.59) | KDM4EL3MBTL1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL27427211 | 0.80 | NR4A1 (0.62) | HPGDKDM4EL3MBTL1NR4A1NR4A2 | |
| SCHEMBL29262289 | 0.79 | NR4A1 (0.61) | HPGDKDM4EL3MBTL1NR4A1NR4A2 | |
| Potassium SCHEMBL6929965 | 0.79 | NR4A1 (0.61) | HPGDKDM4EL3MBTL1NR4A1NR4A2 | |
| SCHEMBL11422834 | 0.79 | NR4A1 (0.61) | HPGDKDM4EL3MBTL1NR4A1NR4A2 | |
| SCHEMBL14672373 | 0.79 | NR4A1 (0.61) | HPGDKDM4EL3MBTL1NR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117915918-A | Soluble adenylate cyclase (sAC) inhibitors and uses thereof | 康奈尔大学 | 2024-04-19 | — | — | CN | disclosed |