SCHEMBL29223003

SCHEMBL29223003

Cc1c(C(=O)O)cccc1C(C)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
PTGS2 P35354 1/20 0.49
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
TSHR P16473 1/20 0.44
CDC25B P30305 1/20 0.44
ATM Q13315 1/20 0.44
DHODH Q02127 2/20 0.43
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42
RXRG P48443 1/20 0.42
ACMSD Q8TDX5 3/20 0.41
USP2 O75604 1/20 0.41
HNF4A P41235 3/20 0.40
DHFR P00374 1/20 0.40
MCL1 Q07820 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29222890 0.90 PTGS2 (0.55) PTGS2ALDH1A1GAAKMT2ATDP1
SCHEMBL29222845 0.80 PTGS2 (0.47) NPC1RAB9APTGS2ALDH1A1KMT2A
SCHEMBL584940 0.79 ALDH1A1 (0.55) ALDH1A1GAAKMT2ATDP1
Biphenyl SCHEMBL27319576 0.79 NPC1 (0.60) NPC1RAB9APTGS2ALDH1A1KMT2A
SCHEMBL29223121 0.79 PTGS2 (0.46) PTGS2ALDH1A1DHODHACMSDHNF4A
SCHEMBL1535968 0.78 TSHR (0.53) PTGS2ALDH1A1KMT2ATDP1TSHR
SCHEMBL28017583 0.77 NPC1 (0.57) NPC1RAB9APTGS2ALDH1A1KMT2A
SCHEMBL246025 0.76 TSHR (0.51) NPC1RAB9APTGS2ALDH1A1GAA
SCHEMBL5888693 0.76 ALDH1A1 (0.49) ALDH1A1GAAKMT2ATDP1TSHR
SCHEMBL312797 0.76 ALDH1A1 (0.50) ALDH1A1GAAKMT2ATDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084596-A Method for hydrogenation functionalization of photocatalytic aryl olefin compound 山东第二医科大学 2024-05-28 CN disclosed