Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28041813 | 0.79 | KDM4E (0.41) | ALDH1A1NPC1RAB9AGAAMAPT | |
| SCHEMBL26403871 | 0.75 | KDM4E (0.41) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL23053815 | 0.74 | TSHR (0.45) | ALDH1A1GAAMAPTATRTSHR | |
| SCHEMBL29608140 | 0.73 | ALDH1A1 (0.38) | ALDH1A1NPC1RAB9AFLT1GAA | |
| SCHEMBL22870683 | 0.73 | ALDH1A1 (0.38) | ALDH1A1NPC1RAB9AFLT1GAA | |
| SCHEMBL22885678 | 0.73 | ALDH1A1 (0.44) | ALDH1A1NPC1RAB9APDGFRBFGFR1 | |
| SCHEMBL4085957 | 0.73 | ABL1 (0.50) | ALDH1A1GAAMAPTTSHRKDM4E | |
| SCHEMBL1341382 | 0.72 | SMN1; SMN2 (0.39) | ALDH1A1NPC1RAB9AGAAMAPT | |
| SCHEMBL2062770 | 0.72 | ALDH1A1 (0.42) | ALDH1A1NPC1RAB9AGAAMAPT | |
| SCHEMBL16965445 | 0.71 | MAPT (0.39) | ALDH1A1NPC1RAB9AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507332-A | Octahydroisoquinolinyl derivatives | UCB生物制药有限责任公司 | 2023-07-28 | — | — | CN | disclosed |