Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1341382 | 0.85 | SMN1; SMN2 (0.39) | KDM4ETSHRATRALDH1A1GAA | |
| SCHEMBL23053815 | 0.84 | TSHR (0.45) | KDM4ETSHRATRALDH1A1GAA | |
| SCHEMBL16965445 | 0.84 | MAPT (0.39) | KDM4ETSHRATRALDH1A1GAA | |
| SCHEMBL31923 | 0.83 | MAPT (0.43) | KDM4ETSHRALDH1A1GAAABL1 | |
| SCHEMBL2695382 | 0.80 | KMT2A (0.55) | KDM4ETSHRALDH1A1GAAMAPT | |
| SCHEMBL4718816 | 0.79 | SMN1; SMN2 (0.41) | TSHRATRALDH1A1MAPTMAPK1 | |
| SCHEMBL29223282 | 0.79 | ALDH1A1 (0.38) | KDM4ETSHRATRALDH1A1GAA | |
| SCHEMBL7411789 | 0.78 | TSHR (0.46) | KDM4ETSHRATRALDH1A1GAA | |
| SCHEMBL3560429 | 0.78 | ALDH1A1 (0.47) | KDM4ETSHRATRALDH1A1GAA | |
| SCHEMBL29416286 | 0.77 | KDM4E (0.49) | KDM4ETSHRATRALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209451-A | 4-amino-6- (heterocyclyl) pyridine-2-carboxylic acid esters and 6-amino-2-2 (heterocyclyl) pyrimidine-4-carboxylic acid esters and their use as herbicides | DOW AGROSCIENCES LLC | 2015-12-30 | — | — | CN | disclosed |