Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | XIAP | P98170 | 1/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.53 |
| ▸ | CPA1 | P15085 | 2/20 | 0.49 |
| ▸ | CPB1 | P15086 | 1/20 | 0.49 |
| ▸ | CPA3 | P15088 | 1/20 | 0.49 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine SCHEMBL9186759 | 0.89 | SLC7A5 (0.71) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Leucine SCHEMBL8740479 | 0.87 | LTA4H (0.60) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL161255 | 0.86 | MME (0.57) | MMENAALAD2L3MBTL1 | |
| SCHEMBL7937827 | 0.86 | MME (0.57) | MMENAALAD2L3MBTL1 | |
| SCHEMBL38480 | 0.86 | MME (0.57) | MMENAALAD2L3MBTL1 | |
| SCHEMBL38479 | 0.86 | MME (0.57) | MMENAALAD2L3MBTL1 | |
| Methamphetamine SCHEMBL6462456 | 0.85 | TAAR1 (0.62) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Methamphetamine SCHEMBL6462454 | 0.85 | TAAR1 (0.62) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Alanine SCHEMBL8347469 | 0.84 | ALPI (0.53) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Alanine SCHEMBL8347467 | 0.84 | ALPI (0.53) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117918557-A | Emulsion, preparation method thereof, filter stick, tobacco product and application | 福建中烟工业有限责任公司 | 2024-04-26 | — | — | CN | disclosed |