Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | ANPEP | P15144 | 1/20 | 0.57 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.57 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.57 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.55 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.55 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.55 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine SCHEMBL9186759 | 0.88 | SLC7A5 (0.71) | LTA4HSLC1A3SLC1A2SLC1A1SLC7A5 | |
| Leucine SCHEMBL8019054 | 0.87 | LTA4H (0.59) | LTA4HANPEPRNPEPDNPEPSLC1A3 | |
| Aspartic Acid SCHEMBL29223446 | 0.87 | ALPI (0.56) | LTA4HSLC1A3SLC1A2SLC1A1SLC7A5 | |
| Alanine SCHEMBL8347469 | 0.86 | ALPI (0.53) | LTA4HSLC7A5ALPIPKMPTGS1 | |
| Alanine SCHEMBL8347467 | 0.86 | ALPI (0.53) | LTA4HSLC7A5ALPIPKMPTGS1 | |
| Leucine SCHEMBL5653346 | 0.85 | LTA4H (0.56) | LTA4HANPEPRNPEPDNPEPSLC1A3 | |
| Phenylalanine SCHEMBL10945389 | 0.85 | SLC7A5 (0.76) | LTA4HANPEPRNPEPDNPEPSLC1A3 | |
| Dl-Phenylalanine SCHEMBL208388 | 0.85 | SLC7A5 (0.76) | LTA4HANPEPRNPEPDNPEPSLC1A3 | |
| D-Phenylalanine SCHEMBL10775923 | 0.85 | SLC7A5 (0.76) | LTA4HANPEPRNPEPDNPEPSLC1A3 | |
| Phenylalanine SCHEMBL2634732 | 0.85 | SLC7A5 (0.76) | LTA4HANPEPRNPEPDNPEPSLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696208-A4 | ORAL DRUG DELIVERY COMPOSITIONS AND METHODS | EMISPHERE TECH INC (US) | 1997-01-29 | — | — | EP | disclosed |
| EP-0696208-A1 | ORAL DRUG DELIVERY COMPOSITIONS AND METHODS | Emisphere Technologies, Inc. (US) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994023767-A1 | ORAL DRUG DELIVERY COMPOSITIONS AND METHODS | EMISPHERE TECHNOLOGIES, INC. (US) | 1994-10-27 | — | — | WO | disclosed |