Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | KCNH3 | Q9ULD8 | 4/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | GPR68 | Q15743 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17173044 | 0.84 | KCNH3 (0.51) | CA1CA2CA9KCNH3APP | |
| SCHEMBL14869710 | 0.81 | CA1 (0.60) | CA1CA2CA9APPNPSR1 | |
| SCHEMBL2456028 | 0.81 | CA1 (0.60) | CA1CA2CA9APPGPR68 | |
| SCHEMBL6838173 | 0.81 | CA9 (0.60) | CA1CA2CA9GPR68NPSR1 | |
| SCHEMBL17220071 | 0.81 | KCNH3 (0.44) | CA1CA2CA9KCNH3APP | |
| SCHEMBL3301514 | 0.80 | NPSR1 (0.74) | CA1CA2CA9KCNH3APP | |
| Hydrochloric Acid SCHEMBL9247173 | 0.78 | NPSR1 (0.72) | CA1CA2CA9KCNH3APP | |
| SCHEMBL29167130 | 0.78 | CA1 (0.57) | CA1CA2CA9KCNH3APP | |
| SCHEMBL17091524 | 0.77 | KCNH3 (0.64) | CA1CA2CA9KCNH3KDM4E | |
| SCHEMBL1390998 | 0.77 | KCNH3 (0.59) | CA1CA2CA9KCNH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986197-A | Triazine hydrazone compound, preparation thereof, pharmaceutical composition containing triazine hydrazone compound and application of pharmaceutical composition | 中国人民解放军海军军医大学 | 2024-05-07 | — | — | CN | disclosed |