Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 5/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23120751 | 0.87 | DDB1 (0.52) | DDB1CRBNALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30913581 | 0.84 | PDK4 (0.51) | DDB1CRBN | |
| SCHEMBL25167744 | 0.84 | PDK4 (0.51) | DDB1CRBN | |
| SCHEMBL29264345 | 0.80 | DDB1 (0.47) | DDB1CRBNALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3993976 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5959136 | 0.76 | ALDH1A1 (0.57) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2241959 | 0.75 | ALDH1A1 (0.67) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL23121268 | 0.75 | ALDH1A1 (0.35) | DDB1CRBNALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL4864624 | 0.75 | ALDH1A1 (0.52) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL16113804 | 0.75 | ALDH1A1 (0.52) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159532-A | Compound with BTK protein degradation activity and medical application thereof | 尤比克斯治疗公司 | 2024-06-07 | — | — | CN | disclosed |