Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 4/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.47 |
| ▸ | QDPR | P09417 | 2/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30952401 | 0.86 | NAMPT (0.47) | DDB1CRBN | |
| SCHEMBL23120751 | 0.83 | DDB1 (0.52) | DDB1CRBNQDPRHPGDSMN1; SMN2 | |
| SCHEMBL29225363 | 0.80 | DDB1 (0.51) | DDB1CRBNHPGDSMN1; SMN2MEN1 | |
| SCHEMBL26621442 | 0.79 | DDB1 (0.59) | DDB1CRBNQDPRHPGDTP53 | |
| SCHEMBL17395676 | 0.76 | QDPR (0.63) | QDPRHPGDTP53SMN1; SMN2MEN1 | |
| SCHEMBL24319286 | 0.75 | GRM1 (0.47) | DDB1CRBN | |
| SCHEMBL31607808 | 0.74 | CRBN (0.67) | DDB1CRBNHPGDTP53MEN1 | |
| SCHEMBL24204354 | 0.74 | CRBN (0.67) | DDB1CRBNHPGDTP53MEN1 | |
| SCHEMBL23121268 | 0.74 | ALDH1A1 (0.35) | DDB1CRBNQDPRSMN1; SMN2MEN1 | |
| SCHEMBL31385819 | 0.73 | DDB1 (0.41) | DDB1CRBNTNKSHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271284-A | Estrogen receptor modulators and uses thereof | 江苏威凯尔医药科技有限公司 | 2024-07-02 | — | — | CN | disclosed |