Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 4/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LGMN | Q99538 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27615189 | 0.89 | GFER (0.46) | GFERCASP6MAPTKDM4EGAA | |
| SCHEMBL28128078 | 0.85 | ALDH1A1 (0.50) | MAPTALDH1A1KMT2APOLBCYP2C9 | |
| SCHEMBL28006179 | 0.84 | GFER (0.55) | GFERCASP6MAPTKDM4EGAA | |
| SCHEMBL28136124 | 0.82 | GFER (0.49) | GFERCASP6MAPTKDM4EGAA | |
| SCHEMBL29225369 | 0.81 | MAPT (0.65) | MAPTSMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL23887597 | 0.80 | GFER (0.48) | GFERCASP6MAPTKDM4EGAA | |
| SCHEMBL7287768 | 0.78 | SMN1; SMN2 (0.55) | GFERCASP6MAPTKDM4EGAA | |
| SCHEMBL27517376 | 0.77 | MAPT (0.48) | GFERMAPTKDM4EGAAALDH1A1 | |
| SCHEMBL5311598 | 0.77 | MAPT (0.53) | GFERCASP6MAPTKDM4EGAA | |
| SCHEMBL27666702 | 0.77 | GFER (0.44) | GFERCASP6MAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159532-A | Compound with BTK protein degradation activity and medical application thereof | 尤比克斯治疗公司 | 2024-06-07 | — | — | CN | disclosed |