Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1165753 | 0.87 | TSHR (0.36) | TSHRALOX15ALOX12SMN1; SMN2LMNA | |
| SCHEMBL3537702 | 0.85 | TSHR (0.38) | TSHRALOX15ALOX12SMN1; SMN2LMNA | |
| SCHEMBL2472068 | 0.84 | PDPK1 (0.37) | TSHRALOX15ALOX12SMN1; SMN2LMNA | |
| SCHEMBL25961101 | 0.80 | TDP1 (0.43) | SMN1; SMN2LMNAHPGDL3MBTL1TDP1 | |
| SCHEMBL11630777 | 0.79 | ALOX15 (0.51) | TSHRALOX15ALOX12SMN1; SMN2NPC1 | |
| SCHEMBL3524389 | 0.78 | ALDH1A1 (0.44) | TSHRLMNAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL29690270 | 0.78 | ALDH1A1 (0.44) | TSHRLMNAMAPTL3MBTL1ALDH1A1 | |
| Acetic Acid SCHEMBL2470427 | 0.78 | SMN1; SMN2 (0.38) | ALOX15ALOX12SMN1; SMN2LMNANPC1 | |
| SCHEMBL26564766 | 0.78 | FFAR1 (0.42) | CDC25B | |
| SCHEMBL734522 | 0.76 | KDM4E (0.47) | TSHRSMN1; SMN2LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108676-B | Benzenesulfonamide compound, pharmaceutical composition and application thereof | 中国药科大学 | 2025-02-07 | — | — | CN | disclosed |
| CN-118108676-A | Benzenesulfonamide compound, pharmaceutical composition and application thereof | 中国药科大学 | 2024-05-31 | — | — | CN | disclosed |