Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 3/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30900316 | 1.00 | SUV39H2 (0.50) | SUV39H2CHRNB2CHRNA4MEN1KMT2A | |
| SCHEMBL30900401 | 0.85 | SUV39H2 (0.40) | SUV39H2ADRB1 | |
| SCHEMBL29226291 | 0.85 | SUV39H2 (0.40) | SUV39H2ADRB1 | |
| SCHEMBL2873572 | 0.83 | SUV39H2 (0.60) | SUV39H2ADRB1ACVR1TGFBR1 | |
| SCHEMBL13024356 | 0.83 | SUV39H2 (0.60) | SUV39H2ADRB1ACVR1TGFBR1 | |
| SCHEMBL29104071 | 0.77 | ADRB1 (0.45) | SUV39H2CHRNB2CHRNA4ADRB1 | |
| SCHEMBL29104004 | 0.77 | ADRB1 (0.45) | SUV39H2CHRNB2CHRNA4ADRB1 | |
| SCHEMBL29104008 | 0.77 | ADRB1 (0.45) | SUV39H2CHRNB2CHRNA4ADRB1 | |
| SCHEMBL30900288 | 0.77 | MEN1 (0.41) | SUV39H2MEN1KMT2ALMNADPP4 | |
| SCHEMBL29226248 | 0.77 | MEN1 (0.41) | SUV39H2MEN1KMT2ALMNADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658987-A | Compounds as PLK1 inhibitors, and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-03-08 | — | — | CN | disclosed |