Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRPC6 | Q9Y210 | 3/20 | 0.40 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30900288 | 1.00 | MEN1 (0.41) | MEN1KMT2AMAPTMAPK1LMNA | |
| SCHEMBL30825164 | 0.86 | CHRM4 (0.37) | MAPTSMN1; SMN2TRPC6CCR1 | |
| SCHEMBL29226259 | 0.86 | CHRM4 (0.37) | MAPTSMN1; SMN2TRPC6CCR1 | |
| SCHEMBL30900298 | 0.85 | TRPC6 (0.42) | TRPC6DPP4CCR1ALDH1A1SUV39H2 | |
| SCHEMBL29226353 | 0.85 | TRPC6 (0.42) | TRPC6DPP4CCR1ALDH1A1SUV39H2 | |
| SCHEMBL29226650 | 0.79 | NR1H2 (0.48) | TRPC6CCR1SUV39H2 | |
| SCHEMBL30900349 | 0.77 | TRPC6 (0.39) | MAPTLMNASMN1; SMN2TRPC6DPP4 | |
| SCHEMBL29227012 | 0.77 | TRPC6 (0.39) | MAPTLMNASMN1; SMN2TRPC6DPP4 | |
| SCHEMBL30900316 | 0.77 | SUV39H2 (0.50) | MEN1KMT2AMAPTMAPK1LMNA | |
| SCHEMBL29226271 | 0.77 | SUV39H2 (0.50) | MEN1KMT2AMAPTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658987-A | Compounds as PLK1 inhibitors, and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-03-08 | — | — | CN | disclosed |