Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29121745 | 0.88 | KMT2A (0.32) | KMT2AALDH1A1MEN1 | |
| SCHEMBL1304622 | 0.79 | — | — | |
| SCHEMBL29226547 | 0.76 | ALDH1A1 (0.40) | KMT2AALDH1A1MEN1TSHRNPC1 | |
| SCHEMBL5063609 | 0.73 | MEN1 (0.33) | KMT2AMEN1 | |
| SCHEMBL7028621 | 0.71 | ALDH1A1 (0.39) | KMT2AALDH1A1MEN1 | |
| SCHEMBL2576614 | 0.70 | ALDH1A1 (0.34) | KMT2AALDH1A1MEN1TSHRNPC1 | |
| SCHEMBL9569737 | 0.70 | KMT2A (0.36) | KMT2AMEN1TSHR | |
| SCHEMBL5535982 | 0.69 | MEN1 (0.37) | KMT2AALDH1A1MEN1 | |
| SCHEMBL1270659 | 0.69 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPK1TP53 | |
| SCHEMBL29226550 | 0.69 | HPGD (0.37) | KMT2AALDH1A1MEN1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659380-A | Hyperbranched polyethylene glycol derivative and preparation method and application thereof | 上海交通大学 | 2024-03-08 | — | — | CN | disclosed |