Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028621 | 0.82 | ALDH1A1 (0.39) | KMT2AMEN1SLC6A3 | |
| SCHEMBL567667 | 0.82 | TSHR (0.40) | KMT2AMEN1SLC6A3TSHR | |
| SCHEMBL12118788 | 0.82 | TSHR (0.40) | KMT2AMEN1SLC6A3TSHR | |
| SCHEMBL5535982 | 0.79 | MEN1 (0.37) | KMT2AMEN1SLC6A3 | |
| SCHEMBL8043855 | 0.78 | MEN1 (0.33) | KMT2AMEN1 | |
| SCHEMBL5063609 | 0.77 | MEN1 (0.33) | KMT2AMEN1 | |
| SCHEMBL8322401 | 0.76 | MEN1 (0.34) | KMT2AMEN1TSHR | |
| SCHEMBL29226547 | 0.76 | ALDH1A1 (0.40) | KMT2AMEN1TSHR | |
| SCHEMBL2739848 | 0.75 | — | — | |
| SCHEMBL13969981 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236426-B | Process for preparing 2,4, 5-trisubstituted 1,2, 4-triazolones | 拜耳股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-112236426-A | Process for preparing 2,4, 5-trisubstituted 1,2, 4-triazolones | 拜耳股份有限公司 | 2021-01-15 | — | — | CN | disclosed |
| EP-0529854-A2 | Tetrahydroindazole, tetrahydrocyclopentapyrazole, and hexahydrocycloheptapyrazole compounds and their use as HMG-COA reductase inhibitors | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-03-03 | — | — | EP | disclosed |