Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23768796 | 0.79 | ITGB3 (0.56) | BRD4L3MBTL1ITGB3ITGA2B | |
| SCHEMBL30343028 | 0.79 | ITGB3 (0.56) | BRD4L3MBTL1ITGB3ITGA2B | |
| SCHEMBL30248682 | 0.78 | L3MBTL1 (0.48) | BRD4L3MBTL1ITGB3ITGA2BSCN9A | |
| SCHEMBL29979065 | 0.74 | BRD4 (0.55) | BRD4L3MBTL1ITGB3ITGA2BSCN9A | |
| SCHEMBL5914780 | 0.74 | BRD4 (0.55) | BRD4L3MBTL1ITGB3ITGA2BSCN9A | |
| SCHEMBL30248614 | 0.74 | ITGB3 (0.56) | BRD4L3MBTL1ITGB3ITGA2BSCN9A | |
| SCHEMBL5914800 | 0.74 | ITGB3 (0.56) | BRD4L3MBTL1ITGB3ITGA2BSCN9A | |
| SCHEMBL1294844 | 0.74 | GAA (0.45) | BRD4L3MBTL1TSHRHTR6MEN1 | |
| SCHEMBL31411730 | 0.73 | BRD4 (0.54) | BRD4L3MBTL1ITGB3ITGA2BSCN9A | |
| SCHEMBL18497019 | 0.72 | BRD4 (0.58) | BRD4L3MBTL1ITGB3ITGA2BSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019738-A | Small molecule urea derivatives as STING antagonists | 库拉德夫制药私人有限公司 | 2024-05-10 | — | — | CN | disclosed |