Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.74 |
| ▸ | MAPT | P10636 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 3/20 | 0.51 |
| ▸ | CNR2 | P34972 | 3/20 | 0.51 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31618184 | 0.87 | KDM4E (0.72) | KDM4EMAPTKMT2AALDH1A1GAA | |
| SCHEMBL31618209 | 0.87 | KDM4E (0.68) | KDM4EMAPTKMT2AALDH1A1GAA | |
| SCHEMBL6057649 | 0.85 | KDM4E (1.00) | KDM4EMAPTKMT2AALDH1A1GAA | |
| SCHEMBL29227090 | 0.84 | KDM4E (0.56) | KDM4EMAPTKMT2AALDH1A1GAA | |
| SCHEMBL5323114 | 0.80 | KMT2A (0.49) | KDM4EMAPTKMT2AALDH1A1GAA | |
| SCHEMBL28727062 | 0.79 | KDM4E (0.60) | KDM4EMAPTKMT2AALDH1A1GAA | |
| SCHEMBL15020505 | 0.78 | MAPT (0.50) | KDM4EMAPTKMT2AALDH1A1GAA | |
| Fumaric Acid SCHEMBL31618127 | 0.78 | KDM4E (0.59) | KDM4EMAPTKMT2AALDH1A1GAA | |
| SCHEMBL9935250 | 0.77 | LTA4H (0.63) | KDM4EMAPTKMT2ACNR1CNR2 | |
| Trifluoroacetic Acid SCHEMBL31618158 | 0.77 | KDM4E (0.54) | KDM4EMAPTKMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | disclosed |