Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.53 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29227187 | 0.92 | PRMT5 (0.55) | PRMT5WDR77KMT2AMEN1LMNA | |
| SCHEMBL29227150 | 0.88 | LMNA (0.48) | PRMT5WDR77KMT2AMEN1LMNA | |
| SCHEMBL29227158 | 0.87 | LMNA (0.62) | PRMT5WDR77KMT2AMEN1LMNA | |
| SCHEMBL29227202 | 0.87 | LMNA (0.47) | PRMT5WDR77KMT2AMEN1LMNA | |
| Ammonia Solution, Strong SCHEMBL29227205 | 0.83 | LMNA (0.51) | PRMT5WDR77KMT2AMEN1LMNA | |
| SCHEMBL29227098 | 0.82 | PRMT5 (0.48) | PRMT5WDR77KMT2AMEN1LMNA | |
| SCHEMBL29227366 | 0.81 | LMNA (0.42) | PRMT5WDR77KMT2AMEN1LMNA | |
| SCHEMBL30873570 | 0.79 | LMNA (0.65) | PRMT5WDR77KMT2AMEN1LMNA | |
| SCHEMBL29227232 | 0.78 | SMN1; SMN2 (0.44) | PRMT5WDR77KMT2AMEN1LMNA | |
| SCHEMBL30929955 | 0.78 | NPC1 (0.50) | PRMT5WDR77KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | disclosed |