Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.53 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.53 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30873570 | 0.92 | LMNA (0.65) | LMNAKMT2AMEN1KDM4EPRMT5 | |
| SCHEMBL29227153 | 0.87 | PRMT5 (0.53) | LMNAKMT2AMEN1KDM4EPRMT5 | |
| SCHEMBL29227148 | 0.87 | LMNA (0.62) | LMNAKMT2AMEN1KDM4EPRMT5 | |
| SCHEMBL29227248 | 0.81 | PRMT5 (0.79) | LMNAKMT2AMEN1KDM4EPRMT5 | |
| SCHEMBL29227124 | 0.79 | MC4R (0.61) | LMNAKMT2AMEN1KDM4E | |
| SCHEMBL29227187 | 0.79 | PRMT5 (0.55) | LMNAKMT2AMEN1KDM4EPRMT5 | |
| SCHEMBL29227190 | 0.78 | LMNA (0.64) | LMNAKMT2AMEN1KDM4EPRMT5 | |
| SCHEMBL29227169 | 0.78 | LMNA (0.60) | LMNAKMT2AMEN1KDM4EPRMT5 | |
| SCHEMBL30873550 | 0.77 | LMNA (0.57) | LMNAKMT2AMEN1KDM4EMAPT | |
| SCHEMBL20379584 | 0.76 | LMNA (0.67) | LMNAKMT2AMEN1KDM4EPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | disclosed |