Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29227214 | 0.81 | PLA2G1B (0.60) | LMNAKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL21939689 | 0.77 | KDM4A (0.52) | KMT2AMEN1ALDH1A1GAAHDAC10 | |
| SCHEMBL1444314 | 0.76 | HPGD (0.59) | LMNAKMT2AL3MBTL1GAAGRM2 | |
| SCHEMBL30873565 | 0.76 | LMNA (0.49) | LMNAKMT2AMEN1KDM4ENPBWR1 | |
| SCHEMBL29227248 | 0.76 | PRMT5 (0.79) | LMNAKMT2AMEN1KDM4ENPBWR1 | |
| Hydrochloric Acid SCHEMBL27698235 | 0.75 | HPGD (0.58) | LMNAKMT2AL3MBTL1GAAGRM2 | |
| SCHEMBL29227190 | 0.75 | LMNA (0.64) | LMNAKMT2AMEN1KDM4ENPBWR1 | |
| SCHEMBL29227169 | 0.74 | LMNA (0.60) | LMNAKMT2AMEN1KDM4ENPBWR1 | |
| SCHEMBL29227084 | 0.74 | LMNA (0.60) | LMNAKMT2AMEN1KDM4ENPBWR1 | |
| SCHEMBL1654408 | 0.74 | PLA2G1B (0.48) | LMNAMAPTL3MBTL1ALDH1A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | disclosed |