Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 15/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 12/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.34 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.34 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28514407 | 0.91 | F11 (0.43) | F11KLKB1CYP3A4 | |
| SCHEMBL30994984 | 0.88 | F11 (0.43) | F11KLKB1CYP3A4 | |
| SCHEMBL29227906 | 0.88 | F11 (0.43) | F11KLKB1CYP3A4 | |
| SCHEMBL16971396 | 0.83 | F11 (0.41) | F11KLKB1NOTUMCYP3A4 | |
| SCHEMBL30995026 | 0.83 | F11 (0.44) | F11KLKB1NOTUMEEDRBBP4 | |
| SCHEMBL30271754 | 0.83 | F11 (0.41) | F11KLKB1NOTUMCYP3A4 | |
| SCHEMBL29479366 | 0.78 | F11 (0.48) | F11KLKB1CYP3A4 | |
| SCHEMBL21357425 | 0.78 | F11 (0.48) | F11KLKB1CYP3A4 | |
| SCHEMBL24633462 | 0.77 | F11 (0.46) | F11KLKB1CYP3A4 | |
| SCHEMBL16115569 | 0.75 | KDM4E (0.42) | F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118126046-A | Substituted macrocyclic compound, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-06-04 | — | — | CN | disclosed |