Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 20/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 19/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21357425 | 1.00 | F11 (0.48) | F11KLKB1CYP3A4 | |
| SCHEMBL29227906 | 0.89 | F11 (0.43) | F11KLKB1CYP3A4 | |
| SCHEMBL30994984 | 0.89 | F11 (0.43) | F11KLKB1CYP3A4 | |
| SCHEMBL30656519 | 0.89 | F11 (0.39) | F11KLKB1CYP3A4 | |
| SCHEMBL29089482 | 0.89 | F11 (0.39) | F11KLKB1CYP3A4 | |
| SCHEMBL28514407 | 0.88 | F11 (0.43) | F11KLKB1CYP3A4 | |
| SCHEMBL24633462 | 0.87 | F11 (0.46) | F11KLKB1CYP3A4 | |
| SCHEMBL21357595 | 0.86 | F11 (0.49) | F11KLKB1CYP3A4 | |
| SCHEMBL24633281 | 0.86 | F11 (0.50) | F11KLKB1CYP3A4 | |
| SCHEMBL29697761 | 0.86 | F11 (0.49) | F11KLKB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765452-B1 | PREPARATIVE PROCESS OF TWO 4-{[(2S)-2-{4-[5-CHLORO-2-(1H-1,2,3-TRIAZOL-1-YL)PHENYL]-5-METHOXY-2-OXOPYRIDIN-1(2H)-YL}BUTANOYL]AMINO}-2-FLUOROBENZAMIDE DERIVATIVES | BAYER AG (DE) | 2022-04-13 | — | — | EP | claimed |
| CN-116134025-B | Amide phosphine oxide derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-118406037-B | Triazole derivative and preparation method and application thereof | 四川师范大学 | 2025-02-25 | — | — | CN | disclosed |
| CN-116283750-B | Heterocyclic amide derivative and preparation method and application thereof | 成都泰和伟业生物科技有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-118406037-A | Triazole derivative and preparation method and application thereof | 四川师范大学 | 2024-07-30 | — | — | CN | disclosed |
| CN-117586284-A | Macrocyclic compound, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-111770917-B | Process for the preparation of two compounds | 拜耳股份公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-116283750-A | Heterocyclic amide derivative and preparation method and application thereof | 成都泰和伟业生物科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116134025-A | Amide phosphine oxide derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2023-05-16 | — | — | CN | disclosed |
| WO-2022057858-A1 | AMIDE PHOSPHINE OXIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2022-03-24 | — | — | WO | disclosed |