Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 18/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 8/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | CTRL | P40313 | 1/20 | 0.35 |
| ▸ | CTRB2 | Q6GPI1 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995039 | 1.00 | F11 (0.40) | F11AOC3KLKB1CYP3A4NOTUM | |
| SCHEMBL30994999 | 0.85 | F11 (0.43) | F11KLKB1CYP3A4F2PRSS1 | |
| SCHEMBL29227908 | 0.85 | F11 (0.43) | F11KLKB1CYP3A4F2PRSS1 | |
| SCHEMBL29227912 | 0.82 | MAP4K4 (0.41) | F11AOC3KLKB1CYP3A4NOTUM | |
| SCHEMBL30995005 | 0.82 | MAP4K4 (0.41) | F11AOC3KLKB1CYP3A4NOTUM | |
| SCHEMBL31174061 | 0.81 | F11 (0.38) | F11KLKB1CYP3A4 | |
| SCHEMBL30995002 | 0.76 | FLT3 (0.46) | F11KLKB1NOTUM | |
| SCHEMBL29186015 | 0.75 | F11 (0.43) | F11KLKB1CYP3A4 | |
| SCHEMBL30752469 | 0.75 | F11 (0.43) | F11KLKB1CYP3A4 | |
| SCHEMBL24633366 | 0.75 | NOTUM (0.39) | F11KLKB1CYP3A4NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118126046-A | Substituted macrocyclic compound, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-06-04 | — | — | CN | disclosed |