Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29228200 | 0.94 | DHODH (0.42) | DHODHRIPK1OTUD7BBACE1USP30 | |
| SCHEMBL29228295 | 0.92 | PPIB (0.41) | DHODHRIPK1HRH3 | |
| SCHEMBL29228445 | 0.87 | F2 (0.41) | DHODHBACE1 | |
| SCHEMBL29121194 | 0.87 | F2 (0.41) | DHODHBACE1 | |
| SCHEMBL29228310 | 0.85 | PPIB (0.43) | DHODHBACE1 | |
| SCHEMBL28828622 | 0.85 | BACE1 (0.41) | DHODHRIPK1OTUD7BBACE1USP30 | |
| SCHEMBL29228287 | 0.85 | RXRA (0.44) | DHODHBACE1SLC13A5 | |
| SCHEMBL29228264 | 0.85 | KIF11 (0.43) | BACE1SLC6A7 | |
| SCHEMBL29121225 | 0.85 | RXRA (0.44) | DHODHBACE1SLC13A5 | |
| SCHEMBL29228350 | 0.84 | RXRA (0.46) | DHODHFFAR1SLC13A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746422-B | Derivatives having 1,2,3, 4-tetrahydronaphthalene moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-03-12 | — | — | CN | claimed |
| CN-114746422-A | Novel derivatives having 1,2,3, 4-tetrahydronaphthalene moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2022-07-12 | — | — | CN | claimed |
| CN-114746422-B | Derivatives having 1,2,3, 4-tetrahydronaphthalene moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-03-12 | — | — | CN | disclosed |
| CN-114746422-A | Novel derivatives having 1,2,3, 4-tetrahydronaphthalene moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2022-07-12 | — | — | CN | disclosed |