SCHEMBL2922997

SCHEMBL2922997

NC(Cc1cccc2ccccc12)[C@@H](C(=O)O)C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ SLC1A3 P43003 1/20 0.42
▸ SLC1A2 P43004 1/20 0.42
▸ SLC1A1 P43005 1/20 0.42
▸ CTNNB1 P35222 1/20 0.41
▸ KMT2A Q03164 3/20 0.40
▸ FABP5 Q01469 3/20 0.39
▸ FABP7 O15540 2/20 0.39
▸ EPHX2 P34913 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.37
▸ MDM4 O15151 1/20 0.37
▸ TP53 P04637 1/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ CASP3 P42574 2/20 0.37
▸ HRH4 Q9H3N8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30089229 0.83 DPP4 (0.39) KMT2AFABP5FABP7EPHX2MDM4
SCHEMBL29036117 0.83 KMT2A (0.45) SLC1A3SLC1A2SLC1A1KMT2AFABP5
SCHEMBL28094649 0.80 SLC1A3 (0.42) SLC1A3SLC1A2SLC1A1KMT2AFABP5
SCHEMBL7128599 0.80 KMT2A (0.47) KMT2AFABP5FABP7EPHX2MDM4
SCHEMBL5035599 0.79 KMT2A (0.40) SLC1A3SLC1A2SLC1A1CTNNB1KMT2A
SCHEMBL29397967 0.79 MDM4 (0.53) MDM4TP53CASP3HRH4
SCHEMBL29547912 0.79 MDM4 (0.53) MDM4TP53CASP3HRH4
SCHEMBL800112 0.79 MDM4 (0.53) MDM4TP53CASP3HRH4
SCHEMBL29401862 0.79 MDM4 (0.53) MDM4TP53CASP3HRH4
SCHEMBL3725031 0.79 MDM4 (0.53) MDM4TP53CASP3HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1675824-B1 SOMATOSTATIN RECEPTOR 1 AND/OR 4 SELECTIVE AGONISTS AND ANTAGONISTS WURSTER SIEGFRIED (FI) 2010-09-29 — — EP disclosed
US-7741362-B2 Somatostatin receptor 1 and/or 4 selective agonists and antagonists SIEGFRIED WURSTER (FI) 2010-06-22 — — US disclosed
US-20100004339-A1 Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists OY JUVANTIA PHARMA LTD. (FI) 2010-01-07 — — US disclosed
US-20070129422-A1 Somatostatin receptor 1 and/or 4 selective agonists and antagonists OY JUVANTIA PHARMA LTD (FI) 2007-06-07 — — US disclosed
EP-1675824-A1 SOMATOSTATIN RECEPTOR 1 AND/OR 4 SELECTIVE AGONISTS AND ANTAGONISTS Oy Juvantia Pharma Ltd (FI) 2006-07-05 — — EP disclosed
WO-2005033069-A1 SOMATOSTATIN RECEPTOR 1 AND/OR 4 SELECTIVE AGONISTS AND ANTAGONISTS OY JUVANTIA PHARMA LTD (FI) 2005-04-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129422-A1 Somatostatin receptor 1 and/or 4 selective agonists and antagonists SSTR4, SSTR1, SSTR3 SLC1A3 525/4885SLC1A2 1014/4885SLC1A1 639/4885
US-20100004339-A1 Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists SSTR4, SSTR1, SSTR3 SLC1A3 525/4885SLC1A2 1014/4885SLC1A1 639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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