Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | FABP7 | O15540 | 2/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8064068 | 0.80 | DPP4 (0.41) | KMT2AEPHX2EPHX1SLC1A3SLC1A2 | |
| SCHEMBL2922997 | 0.79 | SLC1A3 (0.42) | KMT2ACTNNB1EPHX2SLC1A3SLC1A2 | |
| SCHEMBL5707278 | 0.78 | KMT2A (0.36) | KMT2ACTNNB1EPHX2EPHX1MEN1 | |
| SCHEMBL7369838 | 0.76 | KMT2A (0.41) | KMT2AEPHX2ALDH1A1FABP7FABP5 | |
| SCHEMBL13978398 | 0.76 | MDM4 (0.47) | KMT2AEPHX2CASP3 | |
| SCHEMBL8466703 | 0.76 | ALDH1A1 (0.41) | KMT2AALDH1A1MAPTFABP7FABP5 | |
| SCHEMBL30341743 | 0.76 | KMT2A (0.49) | KMT2AEPHX2FABP7FABP5CA1 | |
| SCHEMBL3725031 | 0.76 | MDM4 (0.53) | CASP3 | |
| SCHEMBL800112 | 0.76 | MDM4 (0.53) | CASP3 | |
| SCHEMBL29397967 | 0.76 | MDM4 (0.53) | CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019073-B1 | APOLIPOPROTEIN A-I AGONISTS AND THEIR USE TO TREAT DYSLIPIDEMIC DISORDERS | DASSEUX JEAN-LOUIS (FR) | 2008-01-16 | — | — | EP | disclosed |
| CN-1247254-C | Apolipoprotein A-I agonists and their use in the treatment of dyslipidemic disorders | JEAN LOUIS DASSEUX (US) | 2006-03-29 | — | — | CN | disclosed |
| CN-1198640-C | Apolipoprotein A-I agonists and their use in the treatment of dyslipidemic disorders | DASSEUX JEAN-LOUIS (US) | 2005-04-27 | — | — | CN | disclosed |
| EP-1019073-A4 | APOLIPOPROTEIN A-I AGONISTS AND THEIR USE TO TREAT DYSLIPIDEMIC DISORDERS | DASSEUX JEAN-LOUIS (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-1019074-A4 | APOLIPOPROTEIN A-I AGONISTS AND THEIR USE TO TREAT DYSLIPIDEMIC DISORDERS | DASSEUX JEAN-LOUIS (US) | 2003-07-23 | — | — | EP | disclosed |
| EP-1019010-A4 | APOLIPOPROTEIN A-I AGONISTS AND THEIR USE TO TREAT DYSLIPIDEMIC DISORDERS | DASSEUX JEAN-LOUIS (US) | 2003-07-23 | — | — | EP | disclosed |
| CN-1345245-A | Apolipoprotein A-I agonists and their use to treat dyslipidemias | JEAN LOUIS DASSEUX (US) | 2002-04-17 | — | — | CN | disclosed |
| CN-1280501-A | Apolipoprotein A-I agonists and their use in the treatment of dyslipidemic disorders | JEAN LOUIS DASSEUX (US) | 2001-01-17 | — | — | CN | disclosed |
| CN-1280500-A | Apolipoprotein A-I agonists and their use in the treatment of dyslipidemic disorders | JEAN LOUIS DASSEUX (US) | 2001-01-17 | — | — | CN | disclosed |
| EP-1019010-A1 | APOLIPOPROTEIN A-I AGONISTS AND THEIR USE TO TREAT DYSLIPIDEMIC DISORDERS | Dasseux, Jean-Louis (US) | 2000-07-19 | — | — | EP | disclosed |
| EP-1019074-A1 | APOLIPOPROTEIN A-I AGONISTS AND THEIR USE TO TREAT DYSLIPIDEMIC DISORDERS | Dasseux, Jean-Louis (US) | 2000-07-19 | — | — | EP | disclosed |
| EP-1019073-A1 | APOLIPOPROTEIN A-I AGONISTS AND THEIR USE TO TREAT DYSLIPIDEMIC DISORDERS | Dasseux, Jean-Louis (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999016458-A1 | APOLIPOPROTEIN A-I AGONISTS AND THEIR USE TO TREAT DYSLIPIDEMIC DISORDERS | DASSEUX JEAN LOUIS (US) | 1999-04-08 | — | — | WO | disclosed |
| WO-1999016459-A1 | APOLIPOPROTEIN A-I AGONISTS AND THEIR USE TO TREAT DYSLIPIDEMIC DISORDERS | DASSEUX JEAN LOUIS (US) | 1999-04-08 | — | — | WO | disclosed |
| WO-1999016408-A2 | APOLIPOPROTEIN A-I AGONISTS AND THEIR USE TO TREAT DYSLIPIDEMIC DISORDERS | DASSEUX JEAN LOUIS (US) | 1999-04-08 | — | — | WO | disclosed |