Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.43 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990029 | 0.85 | KMT2A (0.57) | MEN1KMT2APOLBHDAC4MAP4K4 | |
| SCHEMBL34472870 | 0.84 | MEN1 (0.53) | MEN1KMT2APOLBHDAC4CKS1B | |
| SCHEMBL16892019 | 0.83 | PIK3CA (0.59) | MEN1KMT2APIK3CAMAP4K4CKS1B | |
| SCHEMBL34473168 | 0.82 | MEN1 (0.57) | MEN1KMT2APOLBHDAC4GPR119 | |
| SCHEMBL13872069 | 0.82 | KMT2A (0.60) | MEN1KMT2APOLBHDAC4CKS1B | |
| SCHEMBL4298854 | 0.81 | HPGDS (0.59) | MEN1KMT2APOLBHDAC4CKS1B | |
| SCHEMBL28050305 | 0.81 | RAB9A (0.37) | MEN1KMT2ARAB9A | |
| SCHEMBL24756635 | 0.80 | MEN1 (0.51) | MEN1KMT2APOLBHDAC4GPR119 | |
| SCHEMBL3297334 | 0.80 | KMT2A (0.57) | MEN1KMT2APOLBHDAC4CKS1B | |
| SCHEMBL6178837 | 0.80 | MEN1 (0.54) | MEN1KMT2APOLBHDAC4MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146213-A | Benzothiazole pyrimidine amine DYRK2 inhibitor and preparation method and application thereof | 江苏天士力帝益药业有限公司 | 2024-06-07 | — | — | CN | disclosed |