Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 11/20 | 0.62 |
| ▸ | KIT | P10721 | 2/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.58 |
| ▸ | JAK3 | P52333 | 3/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | JAK1 | P23458 | 1/20 | 0.52 |
| ▸ | TYK2 | P29597 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30945086 | 1.00 | PDGFRB (0.62) | PDGFRBKITPDGFRAJAK3JAK2 | |
| SCHEMBL2912785 | 0.81 | PDGFRB (0.78) | PDGFRBKITPDGFRAMEN1KMT2A | |
| SCHEMBL1029982 | 0.80 | PDGFRB (0.61) | PDGFRBKITPDGFRAMEN1KMT2A | |
| SCHEMBL29230307 | 0.80 | KIT (0.65) | PDGFRBKITJAK3 | |
| SCHEMBL1049485 | 0.80 | JAK3 (0.59) | JAK3JAK2JAK1TYK2 | |
| SCHEMBL1045783 | 0.79 | JAK3 (0.55) | PDGFRBKITPDGFRAJAK3JAK2 | |
| SCHEMBL10316846 | 0.79 | JAK3 (0.55) | PDGFRBKITPDGFRAJAK3JAK2 | |
| SCHEMBL2924906 | 0.78 | PDGFRB (0.93) | PDGFRBKITPDGFRA | |
| SCHEMBL7656072 | 0.78 | PDGFRB (0.67) | PDGFRBKITPDGFRAMEN1KMT2A | |
| SCHEMBL29230424 | 0.78 | HPGDS (0.53) | PDGFRBJAK3JAK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146226-A | Pyrrolo [2,3-d ] pyrimidine compound with nitrogen-containing heterocyclic structure, and preparation method and application thereof | 贵州大学 | 2024-06-07 | — | — | CN | disclosed |