Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28434332 | 1.00 | ALDH1A1 (0.45) | ALDH1A1DGKAEPHX2LMNAAPOBEC3A | |
| SCHEMBL12332051 | 0.92 | ALDH1A1 (0.48) | ALDH1A1DGKAEPHX2LMNAAPOBEC3A | |
| SCHEMBL12259968 | 0.86 | TSHR (0.40) | ALDH1A1DGKAEPHX2LMNACA12 | |
| SCHEMBL7273803 | 0.84 | DGKA (0.46) | DGKAEPHX2CA12CA1CA2 | |
| SCHEMBL7361097 | 0.84 | ALDH1A1 (0.41) | ALDH1A1EPHX2LMNAHDAC1HDAC2 | |
| SCHEMBL14482719 | 0.84 | EPHX2 (0.49) | ALDH1A1DGKAEPHX2LMNAHDAC1 | |
| SCHEMBL3914424 | 0.84 | EPHX2 (0.49) | ALDH1A1DGKAEPHX2LMNAHDAC1 | |
| SCHEMBL20450540 | 0.84 | EPHX2 (0.49) | ALDH1A1DGKAEPHX2LMNAHDAC1 | |
| SCHEMBL14482131 | 0.84 | EPHX2 (0.49) | ALDH1A1DGKAEPHX2LMNAHDAC1 | |
| SCHEMBL2380206 | 0.84 | EPHX2 (0.49) | ALDH1A1DGKAEPHX2LMNAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114615981-B | KRAS G12D inhibitors | 米拉蒂治疗股份有限公司 | 2024-04-12 | — | — | CN | disclosed |