Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.52 |
| ▸ | F2 | P00734 | 3/20 | 0.52 |
| ▸ | PLAU | P00749 | 3/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | F2R | P25116 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29232890 | 0.96 | ELANE (0.52) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL29233021 | 0.92 | MAPT (0.49) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL29232906 | 0.86 | ELANE (0.49) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL29232915 | 0.83 | TP53 (0.39) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL29232905 | 0.82 | ELANE (0.49) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL29232911 | 0.78 | TP53 (0.39) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL29232881 | 0.77 | MAPT (0.52) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL29233022 | 0.76 | MAPT (0.50) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL4026837 | 0.76 | MAPT (0.45) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL4030576 | 0.74 | ALDH1A1 (0.47) | MAPTEGFRSRCF2RL3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206560-A | Lipoic acid derivative containing pyridazino indole structure, and preparation method and application thereof | 浙江中医药大学 | 2024-06-18 | — | — | CN | disclosed |