Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 4/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20090384 | 0.80 | KDM1A (0.36) | NOTUM | |
| SCHEMBL12223404 | 0.78 | FEN1 (0.36) | FEN1ALOX5APNOTUMWDR5 | |
| SCHEMBL24203140 | 0.73 | FEN1 (0.33) | FEN1ALOX5APNOTUMWDR5 | |
| SCHEMBL25981340 | 0.72 | NOTUM (0.40) | FEN1ALOX5APNOTUM | |
| SCHEMBL11939197 | 0.72 | FEN1 (0.39) | FEN1ALOX5APNOTUMWDR5 | |
| SCHEMBL18128452 | 0.71 | CA3 (0.36) | — | |
| SCHEMBL3795063 | 0.71 | PDK2 (0.37) | NOTUM | |
| SCHEMBL30154900 | 0.71 | CA3 (0.36) | — | |
| SCHEMBL28204231 | 0.71 | NUDT1 (0.41) | FEN1ALOX5AP | |
| SCHEMBL31013573 | 0.71 | ALOX5AP (0.31) | FEN1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184669-A | Macrocyclic compounds as multi-target kinase inhibitors | 北京伯汇生物技术有限公司 | 2024-06-14 | — | — | CN | disclosed |