Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.58 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 9/20 | 0.51 |
| ▸ | TUBB | P07437 | 9/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 9/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 9/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 9/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 9/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 9/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 9/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 9/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 9/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 9/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 9/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 9/20 | 0.51 |
| ▸ | TUBB2B | Q9BVA1 | 9/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 9/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5991209 | 0.82 | CYP2A6 (0.46) | ERN1PDGFRBPDGFRATUBB4ATUBB | |
| SCHEMBL721861 | 0.80 | ACHE (0.65) | ERN1CA12CA1CA2CA9 | |
| SCHEMBL26414634 | 0.79 | ERN1 (0.50) | ERN1PDGFRBPDGFRATUBB4ATUBB | |
| SCHEMBL27703952 | 0.78 | ERN1 (0.49) | ERN1PDGFRBPDGFRATUBB4ATUBB | |
| SCHEMBL5992568 | 0.76 | GAK (0.48) | ERN1PDGFRBPDGFRATUBB4ATUBB | |
| SCHEMBL24860680 | 0.75 | ACHE (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1308517 | 0.75 | TUBB4A (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1308170 | 0.75 | TUBB4A (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4194370 | 0.75 | BRAF (0.58) | PDGFRBPDGFRACYP2A6KDM4E | |
| SCHEMBL12767024 | 0.74 | ERN1 (1.00) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107898790-B | Antiviral JAK inhibitors for the treatment or prevention of retroviral and other viral infections | 埃默里大学 | 2024-06-21 | — | — | CN | disclosed |